Overview

SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.8
USERS' SCORE
Good
Based on 26 Reviews
8
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend 
134 mg (1 Billion CFU§)
Lactobacillus rhamnosus (GR-1®) 
 
 
Lactobacillus reuteri (RC-14®) 
 
 

Top Medical Research Studies

9
Lactobacillus reduces cold incidences
We evaluated the effectiveness of Lactobacillus casei strain Shirota in reducing upper respiratory tract infections (URTIs) among healthy middle-aged office workers. Over 12 weeks, 96 male participants consumed either fermented milk with LcS or a control milk.

Our findings showed a significant reduction in URTI episodes in those consuming the fermented milk—only 22.4% experienced infections compared to 53.2% in the control group. Furthermore, they had shorter illness durations and better immune responses. Overall, it seems that this daily intake can effectively reduce colds in healthy adults.
Read More
8
Lactobacillus benefits for common cold
We explored the effects of GCL1815, a lactic acid bacterium, on preventing common colds in a double-blind, randomized study with 200 participants.

Those taking GCL1815 experienced fewer symptoms like fever, fatigue, and nasal congestion compared to the placebo group.

The study suggests that GCL1815 activates dendritic cells, potentially enhancing our immune response to viruses. Overall, it appears that GCL1815 could be a promising aid for reducing common cold incidences in healthy adults.
Read More
8
Lactobacillus improves cold symptoms
We explored the effects of LG2055, a type of lactobacillus, on common cold symptoms in a study involving 200 healthy adults. Participants took either a yogurt containing LG2055 or a placebo for 12 weeks while completing daily health surveys.

The findings were promising; those consuming LG2055 reported fewer cold symptoms and showed improved immune markers. This suggests that incorporating LG2055 may help keep us feeling well during cold season by boosting our immune system.
Read More

Most Useful Reviews

9
Good cold effect
14 people found this helpful
Yeast infection and cold effects are very good. It took about four days after taking the medicine for the effects to last a month. I was delighted with the results, thanks to this medicine. If you need a lot of Lactobacillus, I recommend purchasing it for freezing.
Read More
9
Inflammation reduction
3 people found this helpful
This product has been quite helpful for menopausal itching. After taking it, I noticed marked improvements. I opted out of prescribed treatments and, after a week, my examination showed no inflammation. I felt much more comfortable and recommend it to others with similar concerns.
Read More
9
Consistent cold relief
2 people found this helpful
After two years of daily intake, I've noticed a substantial reduction in cold symptoms. I take one pill each morning, and the ingredient compatibility has been ideal for me.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.8
  • All Researches
9
Lactobacillus reduces cold incidences
We evaluated the effectiveness of Lactobacillus casei strain Shirota in reducing upper respiratory tract infections (URTIs) among healthy middle-aged office workers. Over 12 weeks, 96 male participants consumed either fermented milk with LcS or a control milk.

Our findings showed a significant reduction in URTI episodes in those consuming the fermented milk—only 22.4% experienced infections compared to 53.2% in the control group. Furthermore, they had shorter illness durations and better immune responses. Overall, it seems that this daily intake can effectively reduce colds in healthy adults.
Read More
8
Lactobacillus benefits for common cold
We explored the effects of GCL1815, a lactic acid bacterium, on preventing common colds in a double-blind, randomized study with 200 participants.

Those taking GCL1815 experienced fewer symptoms like fever, fatigue, and nasal congestion compared to the placebo group.

The study suggests that GCL1815 activates dendritic cells, potentially enhancing our immune response to viruses. Overall, it appears that GCL1815 could be a promising aid for reducing common cold incidences in healthy adults.
Read More
8
Lactobacillus shows promise for colds
We examined how SBT2055, a lactobacillus treatment, impacts common cold symptoms in healthy adults. In a thorough randomized, double-blind, placebo-controlled trial with 200 participants, those taking SBT2055 reported improved symptom relief compared to the placebo group.

Participants experienced less runny nose, plugged nose, sneezing, sore throat, and chill. This suggests that lactobacillus can enhance immune response, especially in individuals with weakened immunity. Our findings reveal potential benefits of lactobacillus for those suffering from common cold symptoms.
Read More
We explored the impact of yogurt fermented with OLL1073R-1 on immunity against seasonal influenza. Through two controlled trials, we found that participants consuming the yogurt showed higher antibody levels to flu viruses compared to those taking a placebo. Notably, those who consumed the yogurt also reported fewer days of respiratory issues like throat soreness and colds.

This suggests that regular intake of this yogurt can potentially enhance our immune response to influenza vaccines and decrease the duration of cold-like symptoms.
Read More
8
Lactobacillus improves cold symptoms
We explored the effects of LG2055, a type of lactobacillus, on common cold symptoms in a study involving 200 healthy adults. Participants took either a yogurt containing LG2055 or a placebo for 12 weeks while completing daily health surveys.

The findings were promising; those consuming LG2055 reported fewer cold symptoms and showed improved immune markers. This suggests that incorporating LG2055 may help keep us feeling well during cold season by boosting our immune system.
Read More

User Reviews

USERS' SCORE
Good
Based on 26 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Good cold effect
14 people found this helpful
Yeast infection and cold effects are very good. It took about four days after taking the medicine for the effects to last a month. I was delighted with the results, thanks to this medicine. If you need a lot of Lactobacillus, I recommend purchasing it for freezing.
Read More
9
Inflammation reduction
3 people found this helpful
This product has been quite helpful for menopausal itching. After taking it, I noticed marked improvements. I opted out of prescribed treatments and, after a week, my examination showed no inflammation. I felt much more comfortable and recommend it to others with similar concerns.
Read More
9
Consistent cold relief
2 people found this helpful
After two years of daily intake, I've noticed a substantial reduction in cold symptoms. I take one pill each morning, and the ingredient compatibility has been ideal for me.
Read More
9
Effective treatment
1 people found this helpful
After eating, my discharge noticeably decreased. Originally, I experienced a lot of cold along with some unpleasant odour from vaginitis, but this has been effective. Even without intestinal lactobacillus in this product, it remains bearable, as I'm not taking it for bowel issues. I believe women concerned about quality would benefit from it.
Read More
9
Recommended for women
1 people found this helpful
I have tried lactic acid bacteria before, but this is my first experience with female-specific strains. I often had cold symptoms and no itchiness from vaginitis, but as I continued taking this, my cold became clearer and the vaginitis symptoms significantly improved. I feel it’s crucial to take it regularly to avoid recurrent symptoms. When they were severe, I took two tablets instead of one. If I had known how effective it was, I would have bought it sooner. I highly recommend it!
Read More

Frequently Asked Questions

7.5
Cold symptoms reduced
It appears that women's probiotics are primarily bought through Zarrow. I suffered from a severe cold, but after taking them for a few days, my symptoms improved. The eggs are small and easy to swallow. The packaging is slightly altered from before, but the contents seem consistent. I will consume them all and order again.
7
Less cold symptoms
1 people found this helpful
After taking this, I experienced significantly less coldness and reduced secretion. My mother uses it too for frequent vaginitis issues and remains consistent with her intake.
7.5
Improved cold condition
4 people found this helpful
After a month of taking it, I've noticed a significant decrease in cold symptoms. I used to experience odd discolouration but felt better after starting it. It seems to alleviate bladder issues as well, and appears effective for irritable bowel syndrome symptoms. I plan to continue taking it due to its beneficial effects.
9
Good cold effect
14 people found this helpful
Yeast infection and cold effects are very good. It took about four days after taking the medicine for the effects to last a month. I was delighted with the results, thanks to this medicine. If you need a lot of Lactobacillus, I recommend purchasing it for freezing.
9
Consistent cold relief
2 people found this helpful
After two years of daily intake, I've noticed a substantial reduction in cold symptoms. I take one pill each morning, and the ingredient compatibility has been ideal for me.
9
Miraculous reduction
I feel less affected by the common cold after consuming this lactobacillus. It's remarkably reduced my symptoms. I intend to purchase it again.
9
Inflammation reduction
3 people found this helpful
This product has been quite helpful for menopausal itching. After taking it, I noticed marked improvements. I opted out of prescribed treatments and, after a week, my examination showed no inflammation. I felt much more comfortable and recommend it to others with similar concerns.
9
Recommended for women
1 people found this helpful
I have tried lactic acid bacteria before, but this is my first experience with female-specific strains. I often had cold symptoms and no itchiness from vaginitis, but as I continued taking this, my cold became clearer and the vaginitis symptoms significantly improved. I feel it’s crucial to take it regularly to avoid recurrent symptoms. When they were severe, I took two tablets instead of one. If I had known how effective it was, I would have bought it sooner. I highly recommend it!
8
Symptoms improved
It’s really different after consuming this. If I skip it, the common cold flares up frequently, but taking it helps me feel better again.
9
Less cold symptoms
I've noticed a significant reduction in cold symptoms. I’ve always dealt with it, but now if I take this regularly, I hardly experience it. If I miss doses, I still have less cold than before. I am currently taking three capsules and feel it's making a positive difference. I happily recommend it to those around me.
8
Lactobacillus benefits for common cold
We explored the effects of GCL1815, a lactic acid bacterium, on preventing common colds in a double-blind, randomized study with 200 participants.

Those taking GCL1815 experienced fewer symptoms like fever, fatigue, and nasal congestion compared to the placebo group.

The study suggests that GCL1815 activates dendritic cells, potentially enhancing our immune response to viruses. Overall, it appears that GCL1815 could be a promising aid for reducing common cold incidences in healthy adults.
7
Lactobacillus reduces inflammation, not virus
We explored how Lactobacillus rhamnosus affects the response of nasal epithelial cells to rhinovirus, the virus responsible for the common cold.

In our study, nasal cells from healthy adults were treated with different strains of L. rhamnosus before being infected with rhinovirus.

While L. rhamnosus did not alter viral replication or the production of certain inflammatory responses, it did reduce the secretion of pro-inflammatory mediators after infection.

Overall, while it may not stop the virus, L. rhamnosus seems to help dampen some of the cold's inflammatory effects.
9
Lactobacillus reduces cold incidences
We evaluated the effectiveness of Lactobacillus casei strain Shirota in reducing upper respiratory tract infections (URTIs) among healthy middle-aged office workers. Over 12 weeks, 96 male participants consumed either fermented milk with LcS or a control milk.

Our findings showed a significant reduction in URTI episodes in those consuming the fermented milk—only 22.4% experienced infections compared to 53.2% in the control group. Furthermore, they had shorter illness durations and better immune responses. Overall, it seems that this daily intake can effectively reduce colds in healthy adults.

References

  1. Watanabe I, Suzuki N, Takara T. Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study. Nutr Res. 2025;134:99. doi:10.1016/j.nutres.2024.12.004
  2. Wada H, Mawatari T, Saito Y, Azuma N, Iwama Y. Induces Two Types of Dendritic Cell Activation and Effectively Suppresses Onset of the Common Cold: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024;17. doi:10.3390/nu17010101
  3. Yarlagadda T, Zhu Y, Snape N, Carey A, Bryan E, et al. Lactobacillus rhamnosus dampens cytokine and chemokine secretion from primary human nasal epithelial cells infected with rhinovirus. J Appl Microbiol. 2024;135. doi:10.1093/jambio/lxae018
  4. Kobatake E, Iwama Y, Arai T, Tsukisaka Y, Kabuki T. SBT2055 Activates Plasmacytoid Dendritic Cells and Improves Subjective Symptoms of Common Cold in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Parallel-Group Comparative Trial. Nutrients. 2023;15. doi:10.3390/nu15204458
  5. Hemmi J, Makino S, Yokoo T, Kano H, Asami Y, et al. Consumption of yogurt fermented with ssp. OLL1073R-1 augments serum antibody titers against seasonal influenza vaccine in healthy adults. Biosci Microbiota Food Health. 2023;42:73. doi:10.12938/bmfh.2022-037
  6. Kobatake E, Iwama Y, Arai T, Shioya N, Kise M, et al. Intake of SBT2055 improves subjective symptoms of common cold during winter season in healthy adults: A randomized, double-blind, placebo-controlled parallel-group comparative study. Front Nutr. 2022;9:1063584. doi:10.3389/fnut.2022.1063584
  7. Gelardi M, La Mantia I, Drago L, Meroni G, Aragona SE, et al. A probiotic mixture in patients with upper respiratory diseases: the point of view of the otorhinolaringologist. J Biol Regul Homeost Agents. 2020;34:5.
  8. Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N. Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study. Eur J Nutr. 2020;59:409. doi:10.1007/s00394-019-02137-8
  9. Murata M, Kondo J, Iwabuchi N, Takahashi S, Yamauchi K, et al. Effects of paraprobiotic MCC1849 supplementation on symptoms of the common cold and mood states in healthy adults. Benef Microbes. 2018;9:855. doi:10.3920/BM2017.0197
  10. Zhang H, Yeh C, Jin Z, Ding L, Liu BY, et al. Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate. Synth Syst Biotechnol. 2018;3:113. doi:10.1016/j.synbio.2018.03.001
  11. Gleeson M, Bishop NC, Struszczak L. Effects of Lactobacillus casei Shirota ingestion on common cold infection and herpes virus antibodies in endurance athletes: a placebo-controlled, randomized trial. Eur J Appl Physiol. 2016;116:1555. doi:10.1007/s00421-016-3415-x
  12. Makino S, Sato A, Goto A, Nakamura M, Ogawa M, et al. Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1. J Dairy Sci. 2016;99:915. doi:10.3168/jds.2015-10376
  13. Shida K, Sato T, Iizuka R, Hoshi R, Watanabe O, et al. Daily intake of fermented milk with Lactobacillus casei strain Shirota reduces the incidence and duration of upper respiratory tract infections in healthy middle-aged office workers. Eur J Nutr. 2017;56:45. doi:10.1007/s00394-015-1056-1
  14. Kumpu M, Kekkonen RA, Korpela R, Tynkkynen S, Järvenpää S, et al. Effect of live and inactivated Lactobacillus rhamnosus GG on experimentally induced rhinovirus colds: randomised, double blind, placebo-controlled pilot trial. Benef Microbes. 2015;6:631. doi:10.3920/BM2014.0164
  15. Lehtoranta L, Kalima K, He L, Lappalainen M, Roivainen M, et al. Specific probiotics and virological findings in symptomatic conscripts attending military service in Finland. J Clin Virol. 2014;60:276. doi:10.1016/j.jcv.2014.03.021
  16. King S, Glanville J, Sanders ME, Fitzgerald A, Varley D. Effectiveness of probiotics on the duration of illness in healthy children and adults who develop common acute respiratory infectious conditions: a systematic review and meta-analysis. Br J Nutr. 2014;112:41. doi:10.1017/S0007114514000075
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